Betadex Sulfobutyl Ether Sodium From Binzhou Zhiyuan Cas 182410-00-0

Category:Excipients > Wetting/Solubilizing Agents
Product Name:Betadex Sulfobutyl Ether Sodium From Binzhou Zhiyuan Cas 182410-00-0
CAS No.:182410-00-0
Standard:ChP, USP, EP
Price(USD):usd200-230
Company:Shandong Binzhou Zhiyuan Biotechnology Co., Ltd

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Basic Info

Grade: Injection Grade

Factory Location: Shandong China

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 10000kg/month

Packaging Information: 1kg/bag, 10kg/bag
Delivery Lead Time: 3 working days

Sample Provided: yes

Payment Terms: T/T

DMF No.: 030167

Name:? Betadex sulfobutyl ether sodium ?

Other name: Sulfobutyl Ether-Beta-Cyclodextrin Sodium Salt;Sulfobutyl ether-β-cyclodextrin sodium salt;

CAS: 182410-00-0

Abbreviation: SBEBCD

Molecular formula: C42H70-nO35?(C4H8O3S Na)n?

Molecular weight: 1135+158n

Solubility (in 100cm3?solvent, at 25℃) : Water:>50g ; Methanol:<0.5g ; Acetone:<0.5g

Qaulity: Injection grade? ?

Standard: USP43

Package: 500g/bag , 1kg/bag , 2kg/bag, 10kg/drum or customized

Use : Medical?

Specification:?

Standard			USP43-NF38
ITEMS			CRITERIA
Appearance			White to off-white,amorphous powder.
Solubility			Freely soluble in water,sparingly soluble in methanol,practically insoluble in ethanol, in n-hexane, in 1-butanol, in acetonitrile,in 2-propanol and in ethyl acetate.
Identification	IR		Same absorption bands as USP betadex sulfobutyl ether sodium RS.
	HPLC		The retention time of the major peak of sample solution corresponds to the standard solution.
	Average Degree of Substitution		Conform
	Sodium		Identify test are positive for Sodium
Assay			95.0%~105.0%
Beta?Cyclodextrin			≤0.1%
1,4-Butane?Sultone			≤0.5ppm
Sodium Chloride			≤0.2%
4-Hydroxybutane-1-sulfonic Acid			≤0.09%
Bis(4-sulfobtyl)?Ether?Disodium			≤0.05%
Bacterial?Endotoxins			≤20EU/g
The total aerobic?microbial?count			≤100cfu/g
The total?combined moulds?and?yeasts?count			≤50cfu/g
Escherichia coli			Absence
Clarity?of?Solution			30%(w/v)?solution is clear and essentially?free from particles of foreign matter.
Average Degree of Substitution			6.2~6.9
Peaks?I-X (%peak area)		I	0.0~0.3
		II	0.0~0.9
		III	0.5~5.0
		IV	2.0~10.0
		V	10.0~20.0
		VI	15.0~25.0
		VII	20.0~30.0
		VIII	10.0~25.0
		IX	2.0~12.0
		X	0.0~4.0
pH			4.0~6.8
Water?content			≤10.0%
Packaging and storage			Preserve in well-closed containers,and store at room temperature. Protect from?moisture.

Features and applications:

SBE-β-CD is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.

SBE-β-CD has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.

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If you're looking for the high-quality sulfobutyl ether-beta-cyclodextrin sodium salt, our company must be your best choice. We're one of the leading manufacturers and supplier with rich experience and wide expertise. Please be rest assured to buy the products from our factory.

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