Puma Biotechnology, Inc and Pierre Fabre have entered into an exclusive license agreement under which Pierre Fabre will develop and market NERLYNX® (neratinib) in Europe and in some regions of Africa. In September 2018, the European Commission granted the marketing authorization for NERLYNX® (neratinib) for the extended adjuvant treatment of adult patients with early-stage breast cancer-positive HER2 receptor-positive breast cancer who completed less. a year's previous trastuzumab-based adjuvant therapy.

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