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Basic Info

  • Grade: Pharmaceutical Grade

    Factory Location: Zhongcheng Future Industrial Park, Hangcheng Avenue, Baoan District, Shenzhen

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East,Africa

  • Contract Manufacturing: CRO,CMO

  • Sample Provided: yes

    Payment Terms: L/C

    Trelagliptin succinate Biological Activity

    Description:Trelagliptin(SYR-472) is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). IC50 value:Target: DPP4Two Phase II clinical studies have been completed with Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus. Phase III clinical studies with trelagliptin in Japan to evaluate its safety and efficacy in a once-weekly oral treatment regimen. Currently, all available DPP-4 inhibitors are dosed once-daily. A once-weekly treatment, such as trelagliptin, would provide patients with a convenient treatment alternative and has the potential to improve treatment compliance.

    Molecular Formula:C22H26FN5O6

    Molecular Weight:475.470

    Exact Mass:475.186707

    PSA:171.65000

    LogP:1.23468

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