Sitagliptin hydrochloride

• Quick process with improved ability to control chiral purity
• Green process:
• Lack of any chloro derivatives solvents during whole process
• Flexible PSD
• NTTP below limit

Status	Commercial
Therapeutic cat.	Diabetics
Polymorphic form	Form III
CAS No.	862156-92-1
EU DMF readiness
US DMF readiness

Drug description

Sitagliptin is an oral DPP-4 inhibitor used alongside diet and exercise to enhance glycemic control in individuals with type 2 diabetes mellitus. This medication works by increasing insulin and decreasing glucagon in a glucose-dependent manner, thereby improving blood sugar regulation.

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