JenKem Technology provides large scale GMP manufacture of Methoxy PEG Glycerol (M-PEG-GLC) with high purity (97%, and higher) for commercial pharma applications and clinical trials. Methoxy PEG Glycerol (M-PEG-GLC) is a high-quality activated PEG for Lipid Nanoparticles (LNPs).

LNP drug delivery systems are commonly employed for nucleic acid delivery. LNPs are generally believed to combine with the cell membrane through noncovalent affinity and absorbed by endocytosis. After being absorbed by the cell, the mRNA delivered by LNPs are released to the cytoplasm and express the target protein, escaping from the endocytosis. This technology has been adopted by pharmaceutical companies in the recent years for COVID-19 vaccine manufacture1.

Please visit https://jenkemusa.com/products-for-lnps-and-rna-delivery to learn about our PEG and small molecule product line for LNPs. Please contact us at sales@jenkemusa.com for a quote for large scale GMP manufacture of  Methoxy PEG Glycerol (M-PEG-GLC).