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11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione

Category:Intermediates > Pharmaceutical Intermediates
Product Name:11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione
CAS No.:6870-94-6
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Price(USD):Negotiable
Company:Quanzhou Fortune Biopharma Co.,Ltd.

Basic Info

  • Grade: Pharmaceutical Grade

    Factory Location: Quanzhou

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Sample Provided: no

    Payment Terms: L/C

    Main Uses:

    Anti-inflammatory and immunosuppressant As a glucocorticoid drug, it is used to treat inflammatory diseases (such as arthritis, dermatitis, asthma, etc.) and autoimmune diseases (such as systemic lupus erythematosus) by inhibiting the release of inflammatory mediators (such as prostaglandins, leukotrienes) and immune cell function. Anti-allergy can relieve allergic reactions such as allergic rhinitis or contact dermatitis. Purpose of structural modification The introduction of 6α-methyl is usually to enhance the glucocorticoid activity (anti-inflammatory effect) of the drug and reduce salt corticosteroid side effects (such as water and sodium retention). 11β-hydroxyl is a key group for cortisol-like activity, while the 1, 4-diene structure enhances the affinity with the receptor.

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